Tangerine peel glycoside is one of the active ingredients of orange peel, it has been proved that its structure belongs to phenolic compounds, the properties of colourless crystals or crystalline powder, has a smelly aromatic taste, volatile, insoluble in water, soluble in ethanol, ether and other organic solvents, it has a better therapeutic effect on the mite disease of animals.
Tangeretin is a product that can be obtained with high purity through natural extraction and refining production processes, high purity means better bioavailability.
Tangeretin has been proved to be safe for human body.
Tangeretin has good stability and maintains its activity and effect under different environmental and storage conditions.
Tangeretin has an inhibitory effect on a variety of tumour cells, such as colon cancer, breast cancer, lung cancer and gastric cancer. It has been found that Tangeretin can significantly inhibit the proliferation of human AGS gastric cancer cells, the main mechanism of which may be to inhibit ERK phosphorylation and up-regulate the expression of CyclinB1 protein, so that the cells will be blocked in the S phase and G2/M, and then induce apopxosis of AGS cells through the mitochondrial apopxotic pathway mediated by the p53/p21 pathway and the death recepxor pathway mediated by the Fas/FasL pathway.
Anti-inflammatory Effects
The results of many studies have shown that cellulose inhibits LPS-induced pro-inflammatory cytokines and chemokines in mast cells Cellulose inhibits IgE-mediated phosphorylation of ERK1/2 induced by antigenic stimulation, thereby reducing the release and production of pro-inflammatory mediators in mast cells.
Neuroinflammatory response and oxidative damage is one of the important mechanisms of neuronal cell damage in various diseases such as Parkinson's disease and Alzheimer's disease. Studies have shown that Tangeretin can play a neuroprotective role through anti-inflammatory and antioxidant pathways.
Inhibition of Liver and Kidney Damage
Cisplatin, a chemotherapeutic agent used in the treatment of many tumours, has a more pronounced nephrotoxicity.
Obesity is often characterised by a low-grade inflammatory response and insulin resistance, and the interaction between hypertrophic adipocytes and macrophages exacerbates this pathological change.
Other Effects
Interventional effects of Tangeretin in diabetes, cardiovascular disease and asthma have also been reported.Sundaram et al. observed the effects of Tangeretin on the activity of key enzymes of carbohydrate and glycogen metabolism in a rat model of strepxozotocin-induced diabetes.
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Founded in 2014, Sanyi Chemical has 300 to 350 employees. The company integrates production, sales and service. It focuses on plant extracts, active ingredient monomers, plant powders, natural fruit and vegetable powders, and is dedicated to plant extracts. It is a professional company in R&D and production. Strong technical force, annual output of 500 tonnes, product specifications and stable quality.
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